Multivariable logistic regression analysis revealed that an eGFR< 30 ml.min− 1 (1.73 m2)− 1 at renal biopsy was associated with ANCA associated glomerulonephritis in renal-biopsied RA patients (OR 25.13 [1.07–592.06], p = 0.046) adjusted for age, sex, serum albumin and hemoglobin. This evidence concerns the gene ALB and rheumatoid arthritis.