As shown in Table 1, patients with primary composite adverse events and ICU admission were older, mostly males, had anemia, longer prothrombin time, and activated partial thromboplastin time (aPTT), and had comorbidities such as chronic respiratory diseases, cancer, heart disease, dementia, or advanced chronic kidney disease (stage 4 and 5). The gene discussed is F2; the disease is anemia (phenotype).