AHR and hepatocellular carcinoma: Recombinant human hepatoma (HG2L7.5c1) cells, which contain an AhR-responsive luciferase reporter plasmid under the control of 20 dioxin responsive elements (DREs), respond to AhR agonists with the induction of firefly luciferase in a time-, dose- and AhR-dependent manner [37].