The core 14 genes are correlated with multiple biological processes and pathways, which includes the AGE-RAGE signaling pathway, the interleukin-4 and interleukin-13 signaling pathways, the photodynamic therapy-induced NF-kB survival signaling pathway, the negative regulation of the lipid catabolic process, and pancreatic cancer, which are the top interacting pathways. This evidence concerns the gene RENBP and familial pancreatic carcinoma.