SNX16 and colorectal carcinoma: It is reported that in CRC tissues, the expression of SNX16 is significantly upregulated, and upregulated SNX16 interacts with translation elongation factor 1A2 (eEF1A2) to inhibit the degradation and ubiquitination of eEF1A2, thereby activating c-Myc signaling to promote colorectal tumorigenesis [29].