TP53 and viral infectious disease: Although using gene therapy for a viral infection may seem radical to some, it is noteworthy that the TP53 gene carried by SGT-53 does not incorporate into the genome but is expressed transiently with exogenous p53 detectable in transfected cells within 6 h after intravenous administration, with peak expression of exogenous p53 at 24–48 h and markedly diminished p53 expression at 72 h [93].