In contrast with the present study, where the frequency of anti-VCA IgM was low (1.43%); Larsen et al. [29] and Draborg et al. [30] identified high titers of lytic phase antibodies (Anti-EA and Anti-VCA IgA and IgM), discussing the host’s attempt to control the widespread lytic infection in B and epithelial cells that would culminate in the production of various antibody isotypes [26]. The gene discussed is CD40LG; the disease is infection.