CD40LG and systemic lupus erythematosus: Confirming this finding, Li et al. [28] found that patients with SLE are up to 4 times more likely to have active EBV in plasma compared to healthy controls; reinforcing that the association between EBV and SLE exists and can also be explained by the prevalence of anti-VCA (IgG, IgA and IgM), anti-EBNA1 (IgA) and anti-EA (IgG, IgA, IgM) antibodies in these patients.