The KEGG pathway analysis highlighted that a large number of genes that were up-regulated after infection with V2 were the same as those upregulated in response to Herpes simplex infection (genes Myd88, Irf7, H2-Q7, Casp8, Tlr3, Daxx, C3, H2-Aa, Oas2, Oas3, H2-T22, H2-T23 and Cd74). Here, TLR3 is linked to herpes simplex infectious disease.