There is also evidence from animal studies on streptozocin-induced diabetes in rats that resveratrol supplementation normalized glycemia and reduced proinflammatory Tumor necrosis factor (TNF-α), the Interleukin 1 (IL1b), and the Interleukin 6 (IL-6) levels which were linked with the improvement of insulin sensitivity and the mass and structure of the pancreas β-cells [11,12,13,14,15,16]. Here, TNF is linked to diabetes mellitus.