On the other hand, recent studies found that fecal markers of intestinal inflammation, such as fecal calprotectin, are possibly markers of intestinal barrier permeability, intestinal inflammation, and barrier disfunction; in fact, this is confirmed in our study, as infants with non-IgE-mediated food allergy also showed increased values of fecal calprotectin compared to those of healthy subjects [21]. The gene discussed is IGHE; the disease is food allergy.