INS and gestational diabetes: Recent literature has provided insight into the use of different stereoisomers of inositol or their combination in GDM treatment [2,38], showing an improvement in fetal growth, glycemic control (post-prandial glycemia and insulin doses), and maternal weight gain in women who received DCI 500 mg twice a day vs placebo [38]; remarkably, a significant reduction in HOMA-IR and a lower need for intensified insulin therapy in women exposed to MI and MI plus DCI (2) have also been demonstrated.