Conversely, the strongest overlap of adipocyte hypertrophy-associated transcripts was with adipokine-associated transcripts with 2169 (93.0% of all transcripts significantly associated with adipocyte hypertrophy) for leptin and 804 (34.5%) for adiponectin of which 797 (34.2%) were significant for both leptin and adiponectin. This evidence concerns the gene LEP and cardiac hypertrophy.