In addition, the upregulation of type 2 inflammation is characterized by an stimulus at the level of the airway epithelium that results in the production of alarmins -IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) that stimulate the release of IL-4, IL-5, and IL-13, to activate and potentiate the innate and humoral arms of the immune system that lead to the pathogenic airway remodeling in asthma [10,11,12]. Here, TSLP is linked to asthma.