EP300 and Alzheimer disease: Transcriptome analysis of post-mortem samples from the lateral temporal lobe of AD patients shows increased expression of genes associated with chromatin remodeling (genes encoding histone acetyltransferases CBP (CREBBP), p300 (EP300) and TRRAP (a subunit of the SAGA/ATAC complex), histone deacetylases SIRT1 and HDAC4, histone methyltransferases (CXXC31), and histone demethylases (JMJD6)).