IL1B and nephritis: However, following the findings found by Timoshanko et al. [117] on the contribution of IL-1β in nephritis in anti-GBM, other authors concluded, using a murine model, that only dendritic cells that reside mainly in the tubulointerstitium express pro-IL-1β and therefore they activate NLRP3 and caspase-1 secreting mature IL-1β.