Among the shared downregulated DEGs are several genes that have been implicated in glioblastoma growth, invasion, and survival, including EGR1, CDH5, ABCG2, ASCL1, and CD109.This analysis also identified several shared upregulated DEGs with functions that oppose glioblastoma growth and survival, such as CREBRF, BDNF-AS, and TLR4. The gene discussed is BDNF; the disease is glioblastoma.