Of the 21 underexpressed genes, 13 (AKR1C3, CDHR1, DLL1, DLL3, DPP10, ETNPPL, GDF10, IRX2, LUZP2, P2RY12, SCG3, TNR and VIPR2) are reportedly associated with gliomas (Table 4). This evidence concerns the gene SCG3 and central nervous system cancer.