Of the 21 underexpressed genes, 13 (AKR1C3, CDHR1, DLL1, DLL3, DPP10, ETNPPL, GDF10, IRX2, LUZP2, P2RY12, SCG3, TNR and VIPR2) are reportedly associated with gliomas (Table 4). This evidence concerns the gene IRX2 and glioma.