ATM and ataxia telangiectasia: Supportive of a role for DNA DSBs in the neurodegenerative features of AT, inherited mutations in the nuclease meiotic recombination 11 homolog (MRE11), a protein that collaborates with ATM in the recognition and response to DNA DSBs, results in AT-like disorder (ATLD), a disease that exhibits similar neurological defects as AT [99].