MAPT and frontotemporal dementia: FTD presents high inheritance with more than half of the cases showing a familial history of disease mainly due to mutations in microtubule-associated protein tau (MAPT) and progranulin (GRN) genes, and hexanucleotide (GGGGCC) repeat expansion (HRE) in the first intron of the Chromosome 9 Open Reading Frame (C9ORF)72 [128].