More recently, one study exposed the U251 GBM cell line to different concentrations of GA (1 mM, 2 mM, and 4 mM), and the authors observed that the inhibition of cell proliferation and colony formation, apoptosis stimulation, and significant decrease in p65 protein, which is responsible for the activation of the nuclear factor kappa B (NF-κB) pathway [40]. Here, NFKB1 is linked to glioblastoma.