BECN1 and breast carcinoma: Based on the obtained results (Figure 10), we showed that 24 h exposure of human breast cancer cell lines to Les-3331 causes a decrease in Beclin-1 concentration in comparison with the control, where 7.965 ng/mL (MCF-7 cells) and 3.605 ng/mL (MDA-MB-231 cells) of Beclin-1 was detected.