Similarly to MCF-7 cells, incubation of MDA-MB-231 cancer cells with Les-3331 caused a reduction in LC3A concentration (Figure 8B) to 2.982 ng/mL (1 μM Les-3331) and 1.258 ng/mL (5 μM Les-3331), compared to the control (2.965 ng/mL). The gene discussed is MAP1LC3A; the disease is cancer.