Following this hypothesis, better responses (higher CR and survival rates) has been reported in AML cohorts with different ABCB1 polymorphisms [51,57,59,61,63,65,66,67,68], whereas in other studies, these SNPs showed no influence or a worse response [20,53,54,55,56,58,62,64] (Table 2). The gene discussed is ABCB1; the disease is acute myeloid leukemia.