On the other hand, in a Caucasian cohort, the variant alleles of ABCB1 3435C>T, 2677G>A/T and 1236C>T and their haplotypes were associated with higher organ toxicities (renal, hepatic and neutropenia), as well as with higher induction death [62]. Here, ABCB1 is linked to Decreased total neutrophil count.