To evaluate the antiproliferation potential of TFBPC, four types of human cancer cell lines, including MCF-7 (Her2-positive breast cancers), MDA-MB-231 (triple-negative breast cancers), COLO205 (colon cancers) and SK-OV-3 (ovarian cancers), were tested. The gene discussed is ERBB2; the disease is malignant colon neoplasm.