To develop immune stimulation against tumor cells, Huang et al. relied on the specificity of Galα1-3Galβ1-4GlcNAc-R (αGal) carbohydrate epitope synthesis by endoglin (α1,3-galactosyltransferase—α1,3GT) to express αGal on the surface of cells in the tumor microenvironment. This evidence concerns the gene ENG and neoplasm.