Previously, Kim et al. functionalized liposomes (neutral surface charge) and lipoplexes with anti-EGFR to loaded salmosin and interleukin 12 (IL12) genes for the treatment of human ovarian adenocarcinoma (SKOV-3), lung adenocarcinoma (A549), and breast carcinoma (MCF-7), and mouse melanoma (B16BL6). Here, EGFR is linked to breast carcinoma.