We next used CPB and GBVA10-9 peptide–streptavidin bioconjugates (DL633-SA-peptide), which both showed amino acid sequence-dependent tropism towards hepatoma cells (Figure 2) to determine whether these bioconjugates increased the uptake in vitro by hepatoma cells over that of macrophages. This evidence concerns the gene CPB1 and hepatocellular carcinoma.