CBD inhibits cancer cell migration and invasion, via downregulating the expression of markers, associated with epithelial mesenchymal transition (EMT) and invasion, e.g., MT1–MMP (membrane type 1–matrix metalloproteinase 1), MMP-2, MMP9, PAI-1 (plasminogen activator inhibitor 1), FAK (focal adhesion kinase), Id-1 (Inhibitor of DNA binding-1), and inducing the expression of ICAM-1 and TIMP1 [64,65,66,67,68,69,70,71,72,73,74,75,76,77]. The gene discussed is SERPINE1; the disease is cancer.