METTL3 and hepatocellular carcinoma: Consistent with previous studies showing that METTL3 promotes the survival and invasion of HCC cells [31,46], we found that OE of canonical full-length METTL3-A facilitated the growth and proliferation of HCCLM3 cells, as demonstrated by various assays, including regular cell counting, the CCK-8 assay (Figure 5A), and the MTT assay (Figure 5B, left).