Functional enrichment analysis in KEGG pathways by DIANA-miRPath v.3 revealed that the dysregulated miRNAs were significantly enriched in pathways related to HHT pathogenesis, such as TGFβ, PI3K/AKT/Ras/MAPK [55,56,57,58,59,60], mTOR [61], Hippo [62], and Wnt [63,64] signalling pathways (Figure 3). This evidence concerns the gene TGFB1 and hereditary hemorrhagic telangiectasia.