PTEN and prostate adenocarcinoma: As per the GEO dataset findings, the key genes EGFR, VEGFA, PTEN expression level in prostate adenocarcinoma (PRAD) was significantly lower (p < 0.05) compared to non-tumor prostate tissue and the MYC expression level was significantly higher (p < 0.05) in prostate adenocarcinoma (PRAD) compared to non-tumor prostate tissue verified by the TCGA database (Figure 8B–E).