The top characterized and screened genes including EGFR, MYC, VEGFA, PTEN which are involved in prostate cancer progression, cell proliferation and division, cell cycle signaling, metabolic and signaling pathway regulation, angiogenesis, focal adhesion etc. [40,41,42,43,44] Which makes them further as molecular candidates involved in treatment. This evidence concerns the gene PTEN and Familial prostate cancer.