Besides, Androgen receptor (AR), Sp1, TP53, NF-KB1, STAT3, RELA and signature microRNAs such as miR-21-5p, miR-125a-5p, miR145-5p and miR-155-5p have been reported jointly in the same study for the first time in PCa tissue samples as tumor markers and clinical targets. This evidence concerns the gene TP53 and posterior cortical atrophy.