Moreover, additional novel genes screened in this article (lncRNAs: ZFR, CLK4, FAM98A, ZEB2, DLEU1, LINC00184, and LINC00342; mRNAs: CEP192, INPP5F, STRN3, EPM2AIP1, and TWF1) might provide new targets for treating RA. This evidence concerns the gene ZFR and rheumatoid arthritis.