For lncRNA, Zhang et al. documented that the lncRNA HOTAIR can target downstream miR-138 to inhibit the activation of the NF-κB pathway in LPS-treated chondrocytes, which could alleviate the progression of RA, which indicates the importance of lncRNA–miRNA interactions in RA pathogenesis [19]. The gene discussed is HOTAIR; the disease is rheumatoid arthritis.