Using the TNMplot analysis, DLK2 was upregulated in paired ccRCC tissues compared with paired non-tumor tissues (Figure 2B) (*** p < 0.001), and the expression of DLK2 in the ccRCC tumor was significantly higher than in the kidney from the non-ccRCC donor (Figure 2C) (*** p < 0.001). Here, DLK2 is linked to neoplasm.