The Gene Ontology (GO) analysis for cellular components showed that DLK2 was mainly involved in the positive regulation of the extracellular matrix-, cell-substrate junction-, transcription factor complex-, spliceosomal complex-, nuclear chromatin-, and postsynaptic specialization-associated gene clusters (Figure 8A), and endosome membrane-/vacuolar membrane-/mitochondria inner membrane-/mitochondria matrix-related gene expressions were negatively correlated with the DLK2 level in ccRCC. This evidence concerns the gene DLK2 and nonpapillary renal cell carcinoma.