AKT1 and cancer: Two pathways showed high statistical significance and enrichment ratio among these 95 genes, namely, constitutive signaling by AKT1 E17K in cancer (p-value = 5.94 × 10−7, odds ratio = 32.83) and intrinsic pathway for apoptosis (p-value = 6.94 × 10−7, odds ratio = 21.32 folds).