Considering the other two ncRNA players, DBF4P1, and UBE2SP1, the cell cycle context involves other interactors such as UBE2C, FAM83D and MKI67, together with BUB1B (Mitotic Checkpoint Serine/Threonine Kinase B), which encodes a kinase involved in spindle checkpoint function whose impairment is found across cancers, negatively regulating the interactor PLK1 (Polo Like Kinase 1). This evidence concerns the gene PLK1 and cancer.