Likewise, elevated plasma concentrations of CCL2/MCP-1 and CXCL10/IP-10 were found in arthritic and non-arthritic patients compared to HD, although the arthritic group had higher median values of CXCL10/IP-10 [HD 15 (8–19), without arthritis 38 (28–89), with arthritis 66 (44–116) median and interquartile range (IQR)] (Figure 6a,b). This evidence concerns the gene CCL2 and arthritic joint disease.