However, the results described in this study additionally complement this knowledge with the information that the level of protein carbonyl groups in the case of TBEV co-infection is significantly lower compared to the level of CBO in the plasma of TBE patients, hence the induction of NFkB activity may be lower regardless of the level of its subunits similar in both groups of patients. Here, NFKB1 is linked to tick-borne encephalitis.