GPT and hepatocellular carcinoma: Screening for hepatocellular cancer is also recommended for people infected with HBV and active hepatitis (e.g., elevated serum ALT) and/or high viral load (i.e., >100,000 copies/mL (20,000 international units/mL)), with a family history of hepatocellular cancer, for Asian males over the age of 40, Asian females over the age of 50, and for all those of African descent [24].