After the treatment of PGG or cisplatin for 12 days following H460/CR cell injection into the flank of Balb/c nude mice (Figure 7A), PGG treatment showed no toxicity and weight loss (Figure 7B), and it also suppressed the tumor sizes with an increased expression of caspase 3 (Figure 7C–E). The gene discussed is CASP3; the disease is neoplasm.