DNAJC6 and obesity due to melanocortin 4 receptor deficiency: Our pilot GWAS reported that two genes, mitogen-activated protein kinase, kinase 6 (MAP2K6) and DnaJ Heat shock Protein Family Member C6 (DNAJC6), were distinguishingly related to both the resting metabolic rate (RMR) and body mass index (BMI) as biomarkers of obesity in children.