NCF1 and alcohol abuse: Recently, microRNA-223 was reported to ameliorate ALD symptoms by inhibiting the neutrophil IL-6-p47phox (NADPH oxidase p47phox) oxidative-stress pathway by Man et al., a research team from the American Institute on Alcohol Abuse, concluding that the phosphorylation of p47phox was induced by stimulating hepatocytes with inflammatory cytokine IL-6 [13].