CDK12 and neoplasm: Similarly, the highest scoring target mRNA identified for sdRNA-A24 (also containing two notable 3’UTR complementarities, one bearing 100% complementarity to sdRNA-A24 nucleotides 2 through 18) is a known tumor suppressor mutated in ~6% of patients with metastatic CRPC, CDK12 [41,42] (Figure 5A, bottom).