Pericytes express vascular endothelial growth factor receptor 1 (VEGFR1) [106] and stimulation of retinal pericytes with BC-derived VEGFR1 agonists, VEGF, or PlGF [107], resulting in pericyte vascular ablation, increased vascular leakage, and tissue edema [106]. This evidence concerns the gene FLT1 and breast cancer.