NR2F1 and Bosch-Boonstra-Schaaf optic atrophy syndrome: Interestingly, human NR2F1 shows similar graded expression along neocortical axes [2,7,21,23], but it is still unknown whether BBSOAS patients display analogous defects in the positioning, size and function of primary and secondary visual areas; functional magnetic resonance imaging (fMRI) analysis and brain tractography could help to tackle this issue in future clinical studies.