PICK1 and breast cancer: On the other hand, the effect of the microRNA, miR-615-3p, in promoting the epithelial–mesenchymal transition (EMT) in breast cancer cells was shown to rely on targeting the 3′-untranslated regions of PICK1 causing the inhibition of PICK1 translation and an increase in the downstream signaling of transforming growth factor β (TGFβ) [108].