Alzheimer’s Disease: a genetic analysis addressing the association between the PICK1 gene and the risk of Alzheimer’s disease (AD) in the Chinese Han population identified 7 single nucleotide polymorphisms in the PICK1 gene, with rs149474436 being less and rs397780637 being more frequent in AD patients [84]. This evidence concerns the gene PICK1 and early-onset autosomal dominant Alzheimer disease.