AKT1 and acne: Research conducted, among others, by Mielnik, Monfrecola, and Agamia showed that ‘there is increased phosphoinositide 3-kinase-Akt-mammalian target of rapamycin complex 1 (PI3K-Akt-mTORC1) signaling in the skin of patients with acne vulgaris and that increased PI3K-Akt-mTORC1 signaling induces sebum production.’ Plant sterols derived from Camellia sinensis have demonstrated a therapeutic role in the treatment of acne vulgaris [9,10,11,12].