CRP and rheumatoid arthritis: Thus, in this study of a sample of Russian patients with RA, resistant to methotrexate and treated with olokizumab, associations of polymorphic variants of 19 genes with olokizumab efficacy based on the criteria ACR20, ACR50, and DAS28-CRP were revealed, as well as associations of 11 loci with adverse events during the treatment.