Chr 7 gain/Chr 10 loss was also less prevalent in IDH-wt gliomas ascribed to the NT-1 cluster when compared to NT-2 (28.57% for NT-1 vs 71.66% and 45.94% for NT-2 and NT-4, respectively; p = 3.15 × 10−4 and p = 0.36). The gene discussed is IDH1; the disease is central nervous system cancer.