The exposure of airway epithelial cells to specific triggers (i.e., allergens, viruses or irritants in general) prompts to the production and activation of other cytokines, called alarmins (thymic stromal lymphopoietin—TSLP, IL 25 and IL 33), which are able to start a specific inflammatory cascade and therefore result in poor asthma control [11,12]. The gene discussed is TSLP; the disease is asthma.