ALPP and hepatocellular carcinoma: ALP has also been incorporated into a predicted series formula to predict HCC recurrence after partial hepatectomies, such as the Chinese university prognostic index (CUPI), albumin/alkaline phosphatase ratio (AAPR), ALP plus gamma-glutamyl transpeptidase (GGT)/lymphocyte ratio (AGLR), and GGT-to-ALP ratio [4,5,6], suggesting that ALP is important in different HCC studies.