Evaluating clinical and laboratory findings, Mert et al. reported that leukocytosis, elevated CRP and ESR, the presence of prolonged fever, cough, sore throat, diarrhea, arthritis, non-relapsing EN, and an abnormal chest X-ray were predictors of secondary EN, while recurrent EN predicted primary EN [6]. This evidence concerns the gene CRP and Increased total leukocyte count.