An extract obtained from the defatted seeds of Oenothera paradoxa reduced the cell viability and invasiveness of malignant pleural mesothelioma and induced apoptosis in Caco-2 cells [17,23], while phytosterols isolated from EPO and its main components (β-sitosterol and campesterol) decreased the proliferation of human colon adenocarcinoma cell [24]. This evidence concerns the gene EPO and colon adenocarcinoma.